Korean journal of diabetes

Echocardiographic assessment of the myocardial dysfunction in diabetes | Cardiologia Hungarica
  • Recommended Articles Az utóbbi években egyre több bizonyíték szólt a metabolikus szindróma és a 2-es típusú diabetes mellitus karcinogén hatásáról.
  • Baek, Ji Hyun.

This article has been cited by other articles in PMC. Abstract Recently, research on the processing of raw functional materials with the aim of improving various physiological activities has been conducted.

In this study, we investigated the antioxidant activity of royal jelly RJ hydrolysates obtained from three commercial proteases. Enzyme-treated royal jelly ERJin which the RJ hydrolysates were converted into easy-to-absorb shorter chain monomers through the removal of two known allergen proteins, showed no difference in the content of E hydroxydecenoicacid Korean journal of diabetes or the freshness parameter and showed a significant increase in total free amino acid content.

Hospice & Palliative Care

Moreover, ERJ significantly increased the activity of the antioxidant enzyme superoxide dismutase SOD and the level of the antioxidant glutathione GSH in a dose-dependent manner. Korean journal of diabetes findings indicate that ERJ has high potential as an antioxidant agent for use in human and animal diets. Keywords: antioxidation, enzyme, hydrolysates, royal jelly Introduction Researches have been conducted to develop functional raw materials to improve physiological activity.

For example, enzymatic treatments have been proven to be effective for improving the quality of certain existing raw materials by modifying their structure or redistributing their composition Lebesi and Tzia ; Liu et al. It has been proven that reduction in raw material particle size not only alters structural characteristics, but also improves technological properties when using a raw material in food development Chen et al.

Antioxidant Activity of Royal Jelly Hydrolysates Obtained by Enzymatic Treatment

Enzymatic hydrolysates possess many biological activities as potential physiological modulators. They usually contain various amino acid residues, and the activities are based on amino acid composition.

Recently, studies have reported their possible utility as alternative antioxidants Saiga et al.

cukor cukorbetegség cukor cukor tünetek és kezelés insulinoma

Antioxidant is a broad term defined as any substance that significantly delays or inhibits oxidation of a substrate. Antioxidant agents protect living organisms from oxidative damage, resulting in the prevention of various diseases, such as cancer, cardiovascular diseases, and diabetes Napolitano et al. Therefore, the existence of protective agents against free radicals and other oxidants in living cells is very important.

Szegedi Tudományegyetem

It is becoming important to identify antioxidants from natural sources by modify technique. RJ is a traditional product commonly used as a supplement to protect against diseases. Royal jelly is made by young worker bees and is the sole food for young larvae and queen bee.

Royal jelly is composed of important compounds with biological activities, such korean journal of diabetes free amino acids, proteins, sugars, fatty acids, minerals, and vitamins.

Echocardiographic assessment of the myocardial dysfunction in diabetes

Also it contains physiologically active substances such as hydroxydecenoic acid HAD Suguru Fujiwara et al. It has been reported to have functional effects, such as activation of the autonomic nervous system, antibacterial activity, prevention and alleviation of circulatory diseases, anti-inflammatory and anti-cancer effects Guo et al.

diabétesz kezelésére a szarvak slatina kezelése acetonurium diabetes

However, RJ contains two proteins, one is 47 kDa and the other is 55 kDa, which are considered to be major allergens Rosmilah et al. The patients with sensitivity to RJ showed high serum IgE level. Therefore, many studies have been conducted to solve these problems and cukorbeteg étrend pdf make RJ easier to ingest Kim et al.

  • Int J Mol Sci.
  • Hajdu Máté, Maren Oedven Knutsen oh.

In this study, RJ was converted into an easy-to-absorb shorter chain monomer using three commercial protease enzymes. The objective of this study was to prepare ERJ hydrolysates using protease enzymes and to evaluate the antioxidant effect of ERJ on peritoneal macrophages obtained from mice.

topinamburg például a cukorbetegség kezelésében a leghatékonyabb eszköze diabétesz kezelésére

Proteolytic enzymes, including endo-protease obtained from cultures of Bacillus licheniformis, and endo- and exo-protease obtained from cultures of Aspergilus oryzae, were purchased from Vision Biochem Co. RJ powder was mixed with purified water at a ratio of And then the mixture was added mL of methanol, mixed using ultrasonic waves for 30 min. The supernatant obtained by centrifugation 12, rpm, 10 min with addition of mL of methanol was filtered through a 0.

  1. Kezelésére egy töredéke cukorbetegség
  2. Echocardiographic assessment of the myocardial dysfunction in diabetes | Cardiologia Hungarica
  3. Inzulinszint mérő
  4. Вагоны им не попадались.

Standards were prepared by diluting 17 different kinds of amino acid solutions Pickering Laboratories, Inc. The same amount of each standard solution was injected to prepare a standard curve. All experiments were conducted according to the manufacturer's instructions.

Appreciations to Reviewers for Journal of Korean Medical Science ...

Statistical analysis All values were expressed as mean ± SEM. Results and Discussion Confirmation of allergen protein removal and ingredient content change The water-soluble proteins of RJ have been studied in terms of their characteristics and physiological functions according to size in a total of nine fractions Tamura et al.

Among them, water-soluble protein 1 molecular weight MW : 55 kDa and water-soluble protein 2 MW: 47 kDa have been reported as major proteins causing allergies Yoko et al.

Water-soluble proteins 1 and 2 have been reported to stimulate the secretion of TNF-α, a pro-inflammatory cytokine, in macrophages korean journal of diabetes mice Šimúth et al. Therefore, in this study, we examined whether these allergen-induced proteins were removed and the level of HAD was changed by enzyme treatment.

The electrophoretic patterns of the RJ hydrolysates obtained from the enzyme treatments are shown in Fig. The enzyme treatment also resulted in an increase in the level of total free amino acids due to the decomposition of small molecules of polymer Table 1.

Nevertheless, the level of HDA was not changed by the enzyme treatment Table 1. Therefore, with ERJ, there is no need to worry about the risk of allergies when ingested, and the enzymatic processing of RJ is expected to improve the absorption rate.

Fontos információk